Mood, Stress, Sleep, Adrenal & Emotional Wellness Analysis

Struggling with stress, anxiety, low mood, poor sleep, fatigue, burnout, brain fog, emotional overwhelm, ADHD-related symptoms, or hormone imbalance?

The Advanced Neurotransmitter & Hormone Test is a comprehensive at-home wellness assessment designed to evaluate the relationship between hormones, stress response, adrenal rhythm, sleep regulation, and brain chemistry.

This advanced profile combines saliva hormone testing with dried urine neurotransmitter and diurnal hormone analysis to provide deeper insight into mood regulation, emotional wellbeing, cognitive function, sleep quality, stress physiology, and neuroendocrine balance.

By analysing 49 clinically relevant biomarkers, this test helps identify possible imbalances associated with anxiety, depression, fatigue, insomnia, burnout, mood instability, poor focus, and chronic stress.

Why Neurotransmitters and Hormones Matter

Neurotransmitters are chemical messengers that allow the brain and nervous system to communicate with the body.

Hormones and neurotransmitters constantly interact and influence:

• Mood and emotions
• Stress response
• Sleep quality
• Energy production
• Mental clarity and focus
• Emotional resilience
• Motivation and drive
• Hormonal balance
• Cognitive performance

When these systems become dysregulated, some individuals may experience symptoms such as anxiety, fatigue, low mood, irritability, insomnia, emotional overwhelm, hormonal symptoms, poor concentration, or burnout.

Why This Test Is Different

Unlike basic neurotransmitter or hormone tests, this advanced profile also evaluates:

• Free Cortisol patterns throughout the day
• Free Cortisone levels
• Melatonin metabolism
• Adrenal rhythm
• Daily stress adaptation
• Neurochemical pathway balance

This integrated approach provides a broader picture of neuroendocrine health and stress physiology.

What Does This Test Measure?

LCMS Saliva Hormone Profile

This test measures:

• Estradiol (E2)
• Estriol (E3)
• Estrone (E1)
• Progesterone (Pg)
• Testosterone (T)
• Dehydroepiandrosterone Sulfate (DHEA-S / DS)
• Cortisol (C)

These hormones may influence stress response, mood regulation, sleep quality, motivation, emotional wellbeing, energy levels, and hormonal balance.

LCMS Dried Urine Neurotransmitter Profile

The neurotransmitter analysis includes:

• Tryptophan (Trp)
• Serotonin (5-HT)
• 5-Hydroxyindoleacetic Acid (5-HIAA)
• Gamma-Aminobutyric Acid (GABA)
• Glycine (Gly)
• Taurine (Tau)
• Glutamate (Glu)
• Glutamine (Gln)
• Histidine (His)
• Histamine (HIST)
• N-Methylhistamine (N-MeHist)
• Phenylethylamine (PEA)
• Tyrosine (Tyr)
• Tyramine (Tyra)
• Dopamine (DA)
• Dihydroxyphenylacetic Acid (DOPAC)
• Homovanillic Acid (HVA)
• Norepinephrine (NE)
• Normetanephrine (NMN)
• Epinephrine (Epi)
• Vanillylmandelic Acid (VMA)
• Kynurenine (Kyn)
• Kynurenic Acid (KynAc)
• 3-Hydroxykynurenine (3OHKyn)
• Xanthurenate (Xanth)

Diurnal Hormone & Adrenal Rhythm Markers

This advanced assessment also includes:

• Free Cortisol (FC) ×4
• Free Cortisone (FCn) ×4
• 6-Sulfatoxymelatonin (MT6s) ×4
• Creatinine (Crtn) ×5

These markers help assess:

• Daily cortisol rhythm
• Adrenal stress response
• Sleep-wake patterns
• Stress adaptation
• Melatonin metabolism
• Neuroendocrine balance

Who May Benefit From This Test?

This test may be suitable for individuals experiencing:

• Stress or burnout
• Anxiety or emotional overwhelm
• Low mood
• Poor sleep or insomnia
• Fatigue or low energy
• Brain fog
• Poor concentration
• Mood swings
• ADHD-related symptoms
• PMS or PMDD symptoms
• Hormonal imbalance symptoms
• Low libido
• Chronic stress symptoms
• Emotional exhaustion
• Difficulty coping with stress

Suitable for both adults and children when clinically appropriate.

Why Add Cortisol, Cortisone & Melatonin Testing?

Adding diurnal cortisol, cortisone, and melatonin markers provides deeper insight into:

• Adrenal function
• Daily stress adaptation
• Sleep quality
• Energy regulation
• Emotional resilience
• Hormonal stress response

These markers help evaluate how the body responds to physical, emotional, and mental stress throughout the day.

Advanced LCMS Laboratory Technology

Your samples are analysed using advanced LCMS (Liquid Chromatography–Mass Spectrometry) technology.

This gold-standard laboratory method provides:

• High sensitivity and specificity
• Accurate biomarker detection
• Reliable neurochemical pathway analysis
• Advanced hormone assessment
• Objective biochemical data

LCMS technology is widely recognised for laboratory precision and reliability.

Convenient At-Home Collection

This test is designed for easy home collection with no clinic visit required.

The kit includes:

• Saliva collection tubes
• Dried urine collection strips
• Step-by-step instructions
• Return envelope
• Laboratory requisition forms
• Symptom checklist

Samples are collected throughout the day to assess natural hormone and neurotransmitter rhythms.

Personalised Laboratory Report Included

Your confidential laboratory report includes:

• Easy-to-read biomarker results
• Graphical hormone and neurotransmitter analysis
• Specialist laboratory interpretation
• Literature-referenced clinical insights
• Personalised wellness-focused comments
• Suggested next-step considerations

Results are typically available within 3–5 working days after the laboratory receives your samples.

Key Features

• 49 Biomarkers Included
• Advanced Neurotransmitter & Hormone Analysis
• Diurnal Cortisol & Melatonin Assessment
• LCMS Gold Standard Technology
• Home Sample Collection
• Specialist Interpretation Included
• Private & Confidential Results
• No Additional Laboratory Fees
• UK Delivery Included
• Designed to Support Mood, Stress & Wellness Assessment

Important Information

• Customers are responsible for returning samples to the laboratory
• Laboratory fees are included in the price
• The test kit must be used within 12 months of purchase
• Avoid excessive fluid intake on the day of collection
• Avoid alcohol, nicotine, bananas, pineapple, and walnuts before collection as instructed

Frequently Asked Questions

What is a neurotransmitter test?

A neurotransmitter test measures chemical messengers involved in mood, stress response, sleep, energy, cognition, and emotional wellbeing.

Why combine hormone and neurotransmitter testing?

Hormones and neurotransmitters constantly influence each other. Testing both together may provide broader insight into stress physiology, mood regulation, fatigue, sleep quality, and hormonal balance.

What is diurnal cortisol testing?

Diurnal cortisol testing evaluates how cortisol changes throughout the day, helping assess adrenal rhythm and stress adaptation.

Is this test suitable for stress and anxiety symptoms?

This test is commonly selected by individuals experiencing stress, anxiety, burnout, emotional overwhelm, sleep problems, fatigue, or mood instability.

Do I need to visit a clinic?

No. This is a simple at-home collection test with detailed instructions included.

How long do results take?

Results are typically available within 3–5 working days after the laboratory receives your samples.

Is the report confidential?

Yes. Your report is private and confidential and can be securely accessed online.

Test Info

Test ID: SU-841 | Saliva LCMS Hormones 7 + Dried Urine LCMS Neurotransmitters and Diurnal Hormones I Saliva: E2, E3, E1, Pg, T, DS, C | Urine: Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn(x5), FC(x4), FCn(x4), MT6s(x4)

Sample Types: Saliva & Dried Urine

Technology: Advanced LCMS (Liquid Chromatography–Mass Spectrometry) Laboratory Analysis