Anxiety and Depression Test | Advanced Neurotransmitter & Saliva Hormone Analysis

Comprehensive At-Home Assessment for Mood, Stress, Sleep, Hormonal Balance & Emotional Wellbeing Using Advanced LCMS Laboratory Analysis.

Advanced Brain Chemistry, Mood, Stress, Sleep & Hormone Assessment designed to help identify possible neurotransmitter and hormonal imbalances linked to anxiety, low mood, fatigue, burnout, brain fog, poor sleep, and emotional wellbeing.

Using advanced LCMS laboratory analysis, this comprehensive at-home test combines 26 neurotransmitter markers with 7 saliva hormone biomarkers to provide deeper insights into stress response, mood regulation, cognitive performance, adrenal health, and hormonal balance.

Suitable for adults and children.

Why Test Neurotransmitters & Hormones Together?

Hormones and neurotransmitters constantly interact and influence:

• Mood
• Stress response
• Memory
• Sleep
• Focus
• Emotional wellbeing
• Energy production
• Motivation

For example:

• Chronic stress may disrupt cortisol and dopamine balance
• Oestrogen may influence serotonin activity
• Progesterone may affect GABA function
• Testosterone and DHEA may impact motivation, confidence, and mental performance

Testing both systems together provides a clearer picture of the possible root causes behind ongoing physical and emotional symptoms.

Biomarkers Included

26 LCMS Neurotransmitter Markers

Neurotransmitters Urine Markers – 26 Measurements 

• Tryptophan (Trp)
• Serotonin (5-HT)
• 5-Hydroxyindoleacetic Acid (5-HIAA)
• Gamma-Aminobutyric Acid (GABA)
• Glycine (Gly)
• Taurine (Tau)
• Glutamate (Glu)
• Glutamine (Gln)
• Histidine (His)
• Histamine (HIST)
• N-Methylhistamine (N-MeHist)
• Phenylethylamine (PEA)
• Tyrosine (Tyr)
• Tyramine (Tyra)
• Dopamine (DA)
• 3,4-Dihydroxyphenylacetic Acid (DOPAC)
• Homovanillic Acid (HVA)
• Norepinephrine (NE)
• Normetanephrine (NMN)
• Epinephrine (Epi)
• Vanillylmandelic Acid (VMA)
• Kynurenine (Kyn)
• Kynurenic Acid (KynAc)
• 3-Hydroxykynurenine (3OHKyn)
• Xanthurenate (Xanth)
• Creatinine (Crtn)

These neurotransmitters play important roles in:

• Mood regulation
• Sleep
• Anxiety
• Stress resilience
• Memory
• Cognitive function
• Focus and concentration
• Emotional balance

7 Saliva Hormone Markers

The saliva hormone profile includes:

• Estradiol (E2)
• Estriol (E3)
• Estrone (E1)
• Progesterone
• Testosterone
• DHEA-S
• Cortisol

These hormones may influence:

• Stress response
• Energy levels
• Libido
• Mood stability
• PMS
• Menopause symptoms
• Sleep quality
• Adrenal function

Symptoms & Conditions This Test May Help Investigate

Stress & Adrenal Symptoms

• Burnout
• Fatigue
• High stress
• Poor stress tolerance
• Brain fog
• Sleep difficulties
• Low motivation
• Sugar cravings

Mood & Cognitive Symptoms

• Anxiety
• Low mood
• Depression
• Mood swings
• Poor concentration
• Memory problems
• Mental fatigue
• Panic attacks
• ADHD-related symptoms

Hormonal Symptoms

• PMS
• PMDD
• Low libido
• Menopause symptoms
• Hormonal imbalance
• Irritability
• Hot flushes
• Night sweats

Sleep & Nervous System Symptoms

• Insomnia
• Difficulty falling asleep
• Waking during the night
• Poor sleep quality
• Nervousness
• Hyperactivity

Why Choose LCMS Technology?

This test uses advanced LCMS (Liquid Chromatography–Mass Spectrometry) analysis for improved sensitivity, specificity, and accuracy.

Benefits of LCMS testing:

• High analytical accuracy
• Reliable biomarker detection
• Advanced metabolic pathway analysis
• Better specificity than many conventional testing methods

Key Features

• 33 total biomarkers
• Advanced LCMS laboratory analysis
• Saliva & dried urine testing
• At-home sample collection
• Non-invasive testing
• Suitable for adults and children
• Specialist laboratory interpretation included
• Results available within 3–5 working days after sample arrival at the laboratory
• UK delivery included
• Laboratory fee included — no hidden laboratory charges

How Sample Collection Works

Dried Urine Testing: Four small urine samples are collected throughout the day using dried urine filter cards.

Saliva Testing: Saliva samples are collected at specific times to assess hormone and cortisol patterns accurately. The kit includes:

• Full instructions
• Collection materials
• Requisition forms
• Symptom checklist
• Return shipping guidance

Test Results & Specialist Report

Your secure laboratory report will typically be available within 3–5 working days after the laboratory receives your samples.

Your report includes:

• Easy-to-read biomarker graphics
• Numerical laboratory values
• Specialist PhD interpretation
• Personalised laboratory comments
• Clinical considerations and guidance

Who May Benefit From This Test?

This test may be suitable for individuals experiencing:

• Chronic stress
• Anxiety
• Depression
• Burnout
• Hormonal imbalance
• Sleep problems
• Fatigue
• Mood instability
• Cognitive difficulties
• Poor concentration
• Low motivation
• Brain fog
• Neuroendocrine imbalance

Frequently Asked Questions

Is this test suitable for home use?

Yes. The test is designed for simple at-home saliva and dried urine collection.

Do I need to visit a clinic?

No. Samples can be collected privately at home.

Is the laboratory fee included?

Yes. No additional laboratory fee or tax is required.

How quickly will I receive results?

Results are typically available within 3–5 working days after the laboratory receives your sample.

Is the test suitable for children?

Yes. The neurotransmitter profile is suitable for both adults and children.

What technology does the laboratory use?

Advanced LCMS (Liquid Chromatography–Mass Spectrometry) analysis.