Mood, Stress & Anxiety Test | Neurotransmitter and Cortisol Test (LCMS)

Advanced Neurotransmitter & Cortisol Analysis for Brain Fog, Burnout, Sleep, Focus & Emotional Wellbeing

Do you feel constantly stressed, anxious, emotionally overwhelmed, mentally exhausted, unable to focus, or struggling with poor sleep, brain fog, fatigue, or low motivation? The Mood, Stress & Anxiety Test is an advanced at-home Neurotransmitter & Cortisol assessment designed to provide deeper insight into how stress hormones and brain chemistry may be affecting your emotional wellbeing, sleep quality, cognitive performance, energy levels, and nervous system balance. Combining 4-point salivary cortisol testing with advanced LCMS dried urine neurotransmitter analysis, this comprehensive 30-marker profile measures key biomarkers including serotonin, dopamine, GABA, glutamate, norepinephrine, epinephrine, cortisol, and important neurotransmitter metabolites to help identify possible biochemical imbalances linked to chronic stress, burnout, anxiety, mood swings, poor concentration, insomnia, ADHD-related symptoms, emotional instability, and mental fatigue. Suitable for both adults and children.

What Does This Test Measure?

Neurotransmitters Urine Profile – 26 Measurements

This advanced LCMS neurotransmitter panel includes:

• Tryptophan (Trp)
• Serotonin (5-HT)
• 5-Hydroxyindoleacetic Acid (5-HIAA)
• Gamma-Aminobutyric Acid (GABA)
• Glycine (Gly)
• Taurine (Tau)
• Glutamate (Glu)
• Glutamine (Gln)
• Histidine (His)
• Histamine (HIST)
• N-Methylhistamine (N-MeHist)
• Phenylethylamine (PEA)
• Tyrosine (Tyr)
• Tyramine (Tyra)
• Dopamine (DA)
• 3,4-Dihydroxyphenylacetic Acid (DOPAC)
• Homovanillic Acid (HVA)
• Norepinephrine (NE)
• Normetanephrine (NMN)
• Epinephrine (Epi)
• Vanillylmandelic Acid (VMA)
• Kynurenine (Kyn)
• Kynurenic Acid (KynAc)
• 3-Hydroxykynurenine (3OHKyn)
• Xanthurenate (Xanth)
• Creatinine (Crtn)

Cortisol Saliva Profile – 4 Measurements

• Morning Cortisol
• Noon Cortisol
• Evening Cortisol
• Bedtime Cortisol

Total Measurements: 30 Biomarkers

Results are typically available within 3–5 working days after the laboratory receives your samples.

Your private and confidential laboratory report can be securely viewed and downloaded online through your dedicated password-protected patient portal. Results are accessible to both the patient and the laboratory specialist doctor.

Why Combine Cortisol & Neurotransmitter Testing?

Chronic stress can significantly affect neurotransmitter balance and nervous system function.

Combining cortisol and neurotransmitter analysis provides a deeper understanding of:

• Stress-related neurochemical changes
• Burnout patterns
• HPA axis function
• Adrenal and neurotransmitter interactions
• Energy regulation throughout the day
• Mood and emotional resilience
• Sleep and recovery patterns

This dual assessment helps provide a more comprehensive picture of brain health and stress physiology.

Symptoms Linked To Neurotransmitter & Cortisol Imbalance

You may benefit from testing if you experience:

• Anxiety
• Depression
• Mood swings
• Brain fog
• Fatigue
• Burnout
• Poor concentration
• ADHD symptoms
• Panic attacks
• Chronic stress
• Insomnia or disturbed sleep
• Low motivation
• PMS or PMDD symptoms
• Irritability
• Hyperactivity
• Low libido
• Memory problems
• Emotional imbalance

If you regularly experience several of these symptoms, neurotransmitter or cortisol imbalance may be contributing.

Why Are Neurotransmitters Important?

Neurotransmitters regulate many essential brain and nervous system functions, including:

• Mood and emotional stability
• Stress response
• Sleep–wake cycles
• Motivation and reward pathways
• Focus and concentration
• Memory and cognition
• Appetite regulation
• Pain perception
• Behaviour and impulse control
• Hormonal communication
• Autonomic nervous system functions

Imbalances may affect both mental and physical wellbeing.

Advanced LCMS Gold Standard Technology

This test uses LCMS (Liquid Chromatography Mass Spectrometry), considered one of the most advanced laboratory methods available for neurotransmitter analysis.

Benefits Include:

• High sensitivity and specificity
• Reliable detection of neurotransmitter pathways
• Objective biochemical analysis
• Comprehensive metabolic insight
• Quantitative laboratory-based measurements
• Personalised wellness insights
• Ability to monitor progress over time

Why Choose This Neurotransmitter & Cortisol Test?

• Convenient at-home testing
• Non-invasive saliva and dried urine collection
• Comprehensive 30-marker profile
• Advanced LCMS laboratory analysis
• 4-point cortisol assessment
• Specialist PhD laboratory commentary included
• Personalised clinical interpretation
• Supports targeted nutritional and lifestyle strategies
• Fast laboratory turnaround time
• Free UK delivery included
• Laboratory fee included with no hidden costs

How The Test Works

Step 1 — Collect Samples At Home

Collect:

• 4 saliva samples at specific times during the day
• 4 dried urine samples using collection strips

Detailed instructions are included with the test kit.

Step 2 — Send Samples To The Laboratory

Allow samples to dry fully before returning them to the laboratory following the included instructions.

Step 3 — Receive Your Results

Results are typically emailed within 3–5 working days after the laboratory receives your samples.

Your Personalised Report Includes

• Graphical and numerical biomarker results
• Specialist PhD laboratory interpretation
• Clinical commentary
• Guidance on possible next steps
• Clear explanation of imbalances identified

What Is Included In The Test Kit?

• Test requisition form
• Symptom checklist
• Medical history form
• Collection instructions
• Dried urine collection materials
• Saliva collection materials
• Return envelope
• Shipping instructions

Important Information

• Laboratory fee included
• No hidden laboratory charges
• Customers are responsible for return shipping
• Free UK delivery included
• Test kit valid for 12 months from purchase date

Preparation Guidelines

For best results:

• Maintain normal fluid intake
• Avoid alcohol before testing
• Avoid nicotine before testing
• Avoid bananas, pineapple, and walnuts on the test day

A Functional View Of Brain Health

Urinary neurotransmitter testing does not directly measure neurotransmitters inside the brain. However, it may provide valuable insight into systemic neurotransmitter tone, metabolism, stress physiology, and nervous system regulation.

When neurochemistry becomes imbalanced, symptoms may appear long before conventional testing identifies abnormalities. Objective neurotransmitter and cortisol testing may help provide additional clarity and support more personalised wellness strategies.